https://www.neuro-adx-lab.com/tags/relapse-prediction/Relapse PredictionHugo Blox Builder (https://hugoblox.com)en-usSun, 31 May 2026 00:00:00 +0100https://www.neuro-adx-lab.com/media/logo_hu_9de78bf642a435bd.pnghttps://www.neuro-adx-lab.com/tags/relapse-prediction/https://www.neuro-adx-lab.com/projects/relapse-predict/Sun, 31 May 2026 00:00:00 +0100https://www.neuro-adx-lab.com/projects/relapse-predict/<div style="text-align:center; margin-bottom:2rem;"> <img src="project-full.jpg" alt="RELAPSE-PREDICT project overview" style="width:100%; max-width:1200px;" /> </div> <h2 id="project-overview">Project Overview</h2> <div style="margin-bottom:1.25rem; line-height:1.25;"> <div><strong style="white-space: nowrap;">Neural Markers of Reward Dysregulation in Alcoholism Relapse Prediction</strong></div> <div style="margin-top:0.15rem;"><em>RELAPSE-PREDICT: FCT Exploratory R&D Grant Project (2024.13959.PEX)</em></div> </div> <p style="text-align:justify;">This project aims to identify neurobiological and cognitive-behavioral markers of alcohol use disorder (AUD) and evaluate their utility for predicting relapse after treatment. The project applies a multi-method clinical and translational approach that combines neural, cognitive-behavioral, and physiological measures with a prospective follow-up clinical design. By identifying markers of relapse vulnerability, this project aims to inform more specific targets for prevention and intervention.</p> <h2 id="research-aims">Research Aims</h2> <ul> <li>Identify neurobiological markers of reward dysregulation in AUD</li> <li>Characterize cognitive-behavioral markers associated with relapse risk</li> <li>Evaluate whether multimodal markers predict relapse after treatment</li> <li>Inform targeted prevention and intervention strategies for AUD</li> </ul> <h2 id="methods">Methods</h2> <ul> <li>Neural measures of reward dysregulation and alcohol cue reactivity</li> <li>Cognitive-behavioral assessment of relapse risk</li> <li>Physiological markers relevant to relapse risk</li> <li>Prospective clinical follow-up after treatment</li> </ul> <h2 id="funding">Funding</h2> <p>This work is financed by national funds through FCT – Fundação para a Ciência e a Tecnologia, I.P., under the project 2024.13959.PEX</p> <p>Total funding: 60,000€</p> <p>Project DOI: </p> <div style="display:flex; align-items:center; justify-content:center; gap:1.5rem; margin-top:1.5rem; flex-wrap:wrap;"> <img src="fct-logo-tile.jpg" alt="FCT - Fundação para a Ciência e a Tecnologia logo" style="display:block; width:42%; min-width:240px; max-width:420px; height:auto; border:1px solid #e5e7eb; border-radius:8px; box-sizing:border-box;" /> <img src="republica-portuguesa-logo-tile.jpg" alt="República Portuguesa logo" style="display:block; width:42%; min-width:240px; max-width:420px; height:auto; border:1px solid #e5e7eb; border-radius:8px; box-sizing:border-box;" /> </div> <h2 id="research-team">Research Team</h2> <ul> <li><strong>Jorge Martins</strong>, PI (ISPA-Instituto Universitário)</li> <li><strong>Rajita Sinha</strong>, Co-PI (Yale University)</li> <li><strong>Bruce Bartholow</strong> (University of Iowa)</li> <li><span style="white-space: nowrap;"><strong>Francesco Versace</strong> (The University of Texas MD Anderson Cancer Center)</span></li> </ul> <div style="display:flex; gap:1.5rem; justify-content:center; margin-top:2rem; flex-wrap:wrap;"> <a href="flyer-estudo-1.pdf" style="display:block; width:48%; max-width:500px;"> <img src="flyer-estudo-1.jpg" alt="Recruitment flyer for RELAPSE-PREDICT study 1" style="width:100%; height:auto;" /> </a> <a href="flyer-estudo-2.pdf" style="display:block; width:48%; max-width:500px;"> <img src="flyer-estudo-2.jpg" alt="Recruitment flyer for RELAPSE-PREDICT study 2" style="width:100%; height:auto;" /> </a> </div>